Bioactive Peptide Extracts (BPEs)
What they are
BPEs are not vague botanical extracts. They are molecularly defined, sequence‑mapped, and functionally validated peptide sets liberated from plant proteins. GBP’s proprietary platform unites enzymatic hydrolysis, activity‑guided fractionation, advanced proteomics, and AI‑assisted validation to generate multifunctional ingredients with traceable identity and reproducible performance.
From plant to peptide
- Selective enzymatic release under eco‑sustainable conditions.
- Targeted molecular fractionation enriching bioavailable short peptides.
- Proteomics & AI mapping using next‑generation of Mass Spectrometry equipment for peptide identification and AI for peptide prediction (defines the molecular identity of each batch).
- Functional validation — Whole‑cell proteomics in human dermal fibroblasts, human myoblast and macrophage‑like immune cells confirms pathway shifts aligned to regeneration, hydration, antioxidant defense, and immune resolution.
- Formulation translation: lyophilization, encapsulation, stability guidance for real‑world performance.
Validation across levels
- Molecular: peptide composition mapped with precision proteomics.
- In vitro: fibroblast regeneration, macrophage immune modulation, antioxidant & antimicrobial effects.
- In vivo: safety and efficacy confirmed in murine models with histology and tissue proteomics.
- Translational: applications in cosmetics, nutrition, and preventive health supported by dossiers and IP.
What the results show
- Regeneration & ECM architecture: Collagen I/III, elastin, balanced MMP/TIMP activity → firmness, elasticity, smoother appearance.
- Deep hydration & HA matrix: HA synthesis and AQP3‑linked water flow → longer‑lasting hydration and improved barrier from within.
- Immune balance & resolution: Complement surveillance with natural brakes, autophagy‑lysosome clean‑up → quicker recovery without flare.
- Redox resilience: HO‑1, SOD2, catalase, iron‑handling proteins → protection against pollution and photo‑aging.
- Cardiometabolic support: ACE and DPP‑IV inhibitory motifs → systemic balance for beauty‑from‑within narratives.
Quality, safety, and traceability
- 100% plant origin; no ruminant materials (TSE/BSE paperwork not applicable)
- Allergen‑light by design: enrichment in short peptides and removal of larger protein fragments
- Batch identity traceable via LC–MS/MS peptide fingerprints
- Clean, solvent‑free process suitable for global compliance files
A science defined active, not a generic extract
Our BPEs deliver multifunctional benefits with a single, well‑characterized ingredient—reducing complexity while strengthening claims.